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Change The Story Appeal

A brain tumour diagnosis is devastating. Your gift today can help change what happens next. 

Reggie and his family stand in a garden. Text on the image reads: "Change the story for families like Reggie's. Donate now."

We need to keep pushing for more research and better outcomes for children with brain tumours, because a brain tumour diagnosis is absolutely devastating in every sense.

Kirsty, mum to Reggie who was diagnosed with a brain tumour at just four years old

Every day, an average of 36 people in the UK are diagnosed with a brain tumour. For too many families, the story that follows hasn’t changed enough in decades, with limited treatment options, harsh side‑effects and devastating outcomes. 

Research is the only way we’ll discover kinder, more effective treatments and ultimately find cures for brain tumours. But brain tumours are complex, and research takes time, expertise and funding. 

Across the UK, right now, thousands of families are facing the overwhelming reality of a brain tumour diagnosis. By donating to our Change the Story appeal, you can help create better futures for children like Reggie, and for everyone affected by a brain tumour.


Donate now!

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Reggie's mum holds him while he sleeps. He has a bandage on his face holding his oxygen tube in place.

How will your gift help us change the story?

A gift today helps us tackle brain tumours on three critical fronts:

An illustration of a purple microscope in front of a red pound sign, representing funding for vital brain tumour research

Funding vital research

Survival rates and treatment options for brain tumours have barely improved in decades. Your donation helps us fund pioneering research into kinder, more effective treatments, giving more children and adults access to better options and better outcomes. 

An illustration of a pill bottle and two capsules, representing access to clinical trials for brain tumours

Improving access to clinical trials

Clinical trials can give patients hope when options are limited. Your support helps increase access to trials across the UK, so more families can benefit from the latest research and innovations, just as Reggie did.

A illustration of two people sitting on a sofa, representing support for families

Supporting families and driving change

A brain tumour diagnosis is devastating and isolating. Donations fund our expert support services for families and power our campaigns for policy change, so everyone affected receives the understanding and care they deserve. 


The SIOP-HRMB trial is helping us identify which treatments truly benefit children with medulloblastoma. Every advance we’ve made in treating childhood brain tumours has come through research like this. Clinical trials like this are essential to improve survival while protecting quality of life.

Professor Simon Bailey, SIOP-HRMB international clinical trial lead

Researcher looking into a microscope

Help change the story today

We rely on voluntary donations to continue our work. With your support, we can ensure fewer families are left without options and more children like Reggie have the chance of a better future. 

Learn more about The Brain Tumour Charity

About us

We’re committed to finding new treatments, offering the highest level of support and driving urgent change. Find out how we’re doing this.

Accelerating a Cure

Find out more about how our research strategy, Accelerating a Cure, is moving us further, faster towards a cure.

What we’re funding

Get more information about the research projects that we’re able to fund thanks to your donations and support.