Diffuse Intrinsic Pontine Glioma or 'DIPG' has recently been renamed 'Diffuse Midline Glioma' and is the second most common type of primary, high grade brain tumour in children.
Primary brain tumours are those which originate in the brain rather than having spread there from another part of the body.
DIPG is a type of high grade brain tumour. High grade brain tumours tend to grow quickly and are more likely to spread to other parts of the brain or spinal cord. They are sometimes referred to as being 'malignant' or 'cancerous'.
DIPGs originate in an area of the brain, and more specifically the brainstem, called the pons. The pons is an area deep within the lower part of the brain which is responsible for a number of critical bodily functions, such as breathing, sleeping and blood pressure.
The cause of brain tumours, including DIPG, is not yet known. This can be one of the most difficult things to accept as a parent as it can leave you feeling helpless. Brain tumours are nobody's fault. There is no research that shows that anything you may have done during pregnancy or in your child's early infancy could have caused your child's brain tumour.
The signs of a DIPG vary as the pons and surrounding structures (where DIPGs are located) are responsible for a variety of different body functions. A child with a DIPG may display:
In a relatively small number of cases, growth of a DIPG might block the drainage of cerebrospinal fluid (the fluid which surrounds and nourishes the brain), causing a build up of pressure in the head. This is known as hydrocephalus which is very common in other types of brain tumours. Hydrocephalus can cause symptoms such as headache (especially in the morning), nausea and fatigue.
Not all cases of DIPG are identical and a child might show a combination of these symptoms.
If you have further questions, need to clarify any of the information on this page, or want to find out more about research and clinical trials, please contact our team:
0808 800 0004 (free from landlines and mobiles)
Phone lines open Mon-Fri, 09:00-17:00
You can also join our active online community on Facebook - find out more about our groups.
Our free Brain Tumour Information Pack has been designed to help you feel confident when discussing treatment and care options with your medical team.