Clinical Trials

The Brain Tumour Charity and Cancer Research UK (CRUK) are jointly funding clinical trials for brain tumours.

CRUK offer a number of different clinical trial funding schemes that open throughout the year. All applications are reviewed by CRUK's Clinical Research Committee and are subjected to international, competitive peer review. Applications are assessed based on their scientific merit and strategic importance, taking into consideration comments collected from expert peer reviewers. The Committee meets twice a year. Any application approved through this route will be eligible for support in the NHS via inclusion on the National Institute for Health Research (NIHR) portfolio.

Funding schemes

CRUK offer a number of funding schemes to support clinical trials, whether it be to support interventional research into treatments or to test the viability of larger trials.

Early Phase and Feasibility Study Awards – This scheme supports studies that test the viability of larger trials, including the ability to recruit and/or to explore tolerability or efficacy of treatments.

Prospective Sample Collection Awards – This scheme provides support for the collection of samples within a clinical trial but for which it is not yet possible to generate specific research questions.

Experimental Medicine Award – This award provides funding for studies addressing large, high impact translational questions in association with a clinical trial.

Late Phase Clinical Trial Awards – This scheme supports interventional research into cancer treatment (including systemic treatment, radiotherapy and surgery), with a clinical primary endpoint.

Application process

Application details and key dates for each award are available on the CRUK website.

Assessment criteria

Each award has its own eligibility criteria that can be found on the CRUK website. The strengths of each application will be assessed by CRUK's Clinical Research Committee and used to arrive at an overall score. Only studies scoring above an agreed threshold will be considered for funding by The Brain Tumour Charity and Cancer Research UK. Studies funded by this initiative will be jointly branded by The Brain Tumour Charity and Cancer Research UK.

It is strongly advised that prospective applicants develop their trial design with an NCRI Accredited or UKCRC Registered Clinical Trials Unit and the relevant NCRI Clinical Studies Group(s) well in advance of the submission deadline. Please see the below websites for more details:

Further information

Further information on any of the awards listed on this page is available from CRUK. You are also encouraged to contact a funding manager at CRUK to discuss your proposal before starting your application.