Cancer Research UK and The Brain Tumour Charity have launched the Brain Tumour Awards to help advance our understanding about the biology of the disease and the challenges translating discoveries into treatments.
Each year around 11,400 people in the UK are diagnosed with a brain tumour and just 14% of people survive their disease for 10 or more years.The aim of these awards is to accelerate research in a bold and innovative way that would not be possible through traditional funding schemes.
Researchers can apply for grants up to £10 million for each project over five years. Up to £18 million will be awarded in the first round.
The Brain Tumour Awards address 6 major themes:
Unlocking new insights into brain tumours using neuroscience There
is a wealth of neuroscience research on how the brain works and other
neurological disorders. This theme aims to harness this information to help to
expand our knowledge of how brain tumours begin and progress.
Unpicking brain tumours' biology to design more effective drugs Many of the genetic events that fuel brain tumours have yet
to be discovered. This theme seeks to address the knowledge gap, which could
lead to the discovery of new targets for treatments, and the development of drugs
Exploiting the brain tumour environment to make better treatments Brain tumours are influenced by their surrounding
environment, which is unlike anywhere else in the body. This theme is about
gaining a deep understanding of the cells and tissues around the tumour and the
protective blood-brain barrier**, to inform the development of new ways to
detect and treat the disease.
more accurate ways to study brain tumours Many potential new treatments that have shown promise in lab
research have failed in patients. One of the reasons behind this is that
studies in cells and mice don't always capture what happens in people. The aim
of this theme is to develop better ways to study brain tumours in the lab, to
accelerate the translation of research from bench to bedside.
brain tumour diagnosis to make treatment more personal Many brain tumours are diagnosed based on how the cells look
under the microscope, but this misses other vital pieces of information – such
as genetics – which can influence how the disease will behave. This theme seeks
to develop a more precise way of classifying brain tumours, which will help improve
clinical trials and treatment decisions.
Develop kinder treatments for brain tumours While
some brain tumours grow quickly and need aggressive treatment, others progress
slowly and patients could be spared intensive therapy where it's not needed.
This challenge aims to make treatments kinder for patients with less aggressive
brain tumours, lowering the risk of side effects and improving quality of life.
This is particularly important for children with brain tumours, where long term
side effects can significantly affect quality of life.
Application details and key dates for each award are available on the
Each award has its own eligibility criteria that can be found on the CRUK website. The strengths of each application will be assessed by CRUK's Clinical Research Committee and used to arrive at an overall score. Only studies scoring above an agreed threshold will be considered for funding by The Brain Tumour Charity and Cancer Research UK. Studies funded by this initiative will be jointly branded by The Brain Tumour Charity and Cancer Research UK.
Further information on any of the awards listed on this page is available from CRUK. You are also encouraged to contact a funding manager at CRUK to discuss your proposal before starting your application.