Get your free Information Pack
If you or someone you love has been diagnosed with a brain tumour and you don’t know which way to turn, start with our free Information Pack.
Losartan is a drug commonly used to treat conditions including high blood pressure, heart disease and kidney disease in people with diabetes. You may also hear losartan called by its brand name Cozar®.
NICE do not recommend losartan as a treatment for brain tumours. It is important to speak to your healthcare team before taking any new medications or making changes to your current brain tumour treatment.
There are currently ongoing trials to see if this type of drug could be effective in improving the outcomes of chemotherapy in patients with pancreatic cancer. In pre-clinical trials with mice, scientists discovered that Losartan increased the blood flow within tumours, therefore improving the delivery of chemotherapy.
Losartan is able to cross the blood-brain barrier. A trial was carried out testing the effect of Losartan on rats implanted with glioma cells which appeared to decrease in tumour volume after 30 days compared to those which were not given the drug. Researchers in France began a clinical trial in 2013 “Angiotensin II Receptor Blockers, Steroids and Radiotherapy in Glioblastoma" which has not yet posted results.
Further research is needed.
If you need someone to talk to or advice on where to get help, our Support and Information team is available by phone, email or live-chat.
By taking part in our Improving Brain Tumour Care surveys and sharing your experiences, you can help us improve treatment and care for everyone affected by a brain tumour.
If you have further questions, need to clarify any of the information on this page, or want to find out more about research and clinical trials, please contact our team:
0808 800 0004 (free from landlines and mobiles)
Phone lines open Mon-Fri, 09:00-17:00
You can also join our active online community - Join our online support groups.