Celecoxib (Celebrex®)

Celebrex® is the brand name of a drug known as celecoxib. Celecoxib is a type of drug known as “non-steroidal anti-inflammatory drugs" (NSAIDs).

NICE do not recommend celecoxib as a treatment for brain tumours.

NSAIDs are used as pain relief, to reduce inflammation and reduce temperature. Celebrex® is commonly used to treat arthritis and menstrual cramps.

Celecoxib and brain tumours

A clinical trial was started in 2003 to investigate whether celecoxib could be beneficial for patients with a glioblastoma who were undergoing radiotherapy and taking medicines to manage seizures. It was thought that celecoxib might be able to block the enzymes that are necessary for tumour growth.

The trial was stopped as the results from another study showed that a combination of temozolomide and radiation improved survival while the results of this trial were not showing a significant improvement in results.

Celecoxib is not recommended by NICE for the treatment of brain tumours. It is important to speak to your healthcare team before making any changes to your treatment or taking new medications.

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