Our free Patient Information Pack has been designed to help you feel confident when discussing treatment and care options with your medical team.
Brain tumours are graded 1-4 according to their behaviour, such as the speed at which they are growing, and how likely they are to spread into other areas of the brain. Over time, some brain tumour's behaviour can change and the tumour may become, or come back as, a higher grade tumour.
Confirming the diagnosis of the different grades of brain tumours is done, where possible, by analysing cells from the tumour, taken during a biopsy or during surgery. A neuropathologist examines the cells in the laboratory, looking for particular cell patterns that are characteristic of the different types and grade of brain tumour.
Grade 1 and 2 tumours are low grade, slow growing, relatively contained and unlikely to spread to other parts of the brain. There is also less chance of them returning if they can be completely removed. They are sometimes still referred to as 'benign'.
The term 'benign' is less used nowadays as this can be misleading. These low grade brain tumours can still be serious.
This is because the tumour can cause harm by pressing on and damaging nearby areas of the brain, due to the limited space capacity of the skull. They can also block the flow of the cerebrospinal fluid (CSF) that nourishes and protects the brain, causing a build-up of pressure on the brain.
Grade 3 and 4 tumours are high grade, fast growing and can be referred to as 'malignant' or 'cancerous' growths.
They are more likely to spread to other parts of the brain (and, rarely, the spinal cord) and may come back, even if intensively treated. They cannot usually be treated by surgery alone, but often require other treatments, such as radiotherapy and/or chemotherapy.
Some tumours contain a mixture of cells with different grades. The tumour is graded according to the highest grade of cell it contains, even if the majority of it is low grade.
Accurate diagnosis is important as it allows your medical team to give you information about how the tumour could behave in the future, and also to recommend treatment options. This could include a clinical trial.
Sometimes confirming the grade can be difficult as some low grade and high grade tumours can look very similar.
Whether you've been diagnosed with a brain tumour, or it's a family member or friend, we are here to help. We offer a wide range of inclusive and accessible information and services for everyone affected by a brain tumour, whether it's low or high grade, adult or child.
Page last reviewed: 05/2015
Next review due: 05/2018
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