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A psychological/ emotional condition that involves the body, mood, thoughts and affects the way a person eats and sleeps for more than a few weeks. It is characterised by feelings of sadness, loneliness, despair, low self-esteem, withdrawal from social contact, loss of appetite and insomnia. Bipolar depression: Experiencing mood swings alternating between elation (mania) and depression. The mood swings can last for weeks at a time and cause significant work and relationship problems.