Dr Rameen Beroukhim
Investigating transcription factors in development
We are the leading funder of brain tumour research in the UK, committing over £50 million to date on pioneering projects that will help adults and children with brain tumours.
We fund research through a competitive, fair and transparent process of best practice called peer review to ensure we only select the very best research that will have a real impact on those affected by brain tumours.
We're pleased to share our most recent research awards. Our Scientific Advisory Board told us that these are the highest quality grants with the best chance of success. We look forward to seeing their progress in the coming months and years.
Dr Beroukhim’s team are doing an in-depth analysis of two transcription factors, one that they suspect drives low grade brain tumours and the other that may drive high grade brain tumours.
Ultimately they’ll be looking for ways to use drugs to return transcription to normal levels, and stop tumour growth.
One of our ongoing grants identified a protein called SRC that may be driving group 4 medulloblastomas in children. This type of tumour has been notoriously difficult to study and to treat. This new research will delve into the role of SRC in starting and motivating tumour growth, and the team will be using sophisticated lab models to test a new drug to target it.
As part of our research strategy, A Cure Can't Wait, we have established various funding opportunities to achieve our goals of doubling survival and halving the harm caused by a brain tumour. More information about the different types of grants we fund can be found below: