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Using drugs and gels to bypass the blood brain barrier

Fast facts

  • Official title: Overcoming the blood brain barrier: supramolecular hydrogels for combination drug delivery in GBM resection cavities
  • Lead researcher: Professor Colin Watts
  • Where: University of Cambridge
  • When: May 2017 - February 2020
  • Cost: £100,000
  • Research type: Adult, Glioblastoma (High Grade), Academic

Dr Colin Watts and his team at the University of Cambridge are testing drug-containing gels as a new delivery method for the treatment of high grade brain tumours.

They will begin by determining the most effective chemotherapy and radiotherapy drug combinations to target genetically different cells within glioblastoma tumours. The team will then test these combinations by loading them in to the gel and injecting them into models of surgical cavities.

This project plays an important role in determining whether hydrogel drug delivery is a feasible treatment option to avoid the difficulty of getting drugs across the blood brain barrier.

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