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Lapatinib (Tyverb®)

Lapatinib is a drug used for targeted therapy in women with breast cancer that has spread to another part of the body. It may also be known by its brand name Tyverb®.

This type of drug works by targeting a protein called HER2 which is found in some breast cancers and causes the cancer cells to grow. Lapatinib works by stopping the cells growing and dividing to spread. It is given alongside other drugs to treat breast cancer including chemotherapy.

NICE does not currently recommend lapatinib. This means that it is not routinely available on the NHS but it may be given as part of a clinical trial. It is important you speak to your healthcare team before making any changes to your treatment or taking new medicines.

Lapatinib and brain tumours

Some women with breast cancer can develop brain metastases. A phase two clinical trial was carried out to test the effect of lapatinib in women with HER2 positive breast cancer who had developed a secondary brain tumour. The clinical trial recommended that further research be carried out.

Make the right choices for you

Our Step by Step interactive guide outlines what happens following a brain tumour diagnosis. It also answers your questions and helps you to understand what to expect.

If you have further questions, need to clarify any of the information on this page, or want to find out more about research and clinical trials, please contact our team:
Support and Information Services
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A member of our Support & Information Team provides support over the phone to somebody affected by a brain tumour diagnosis

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If you need someone to talk to or advice on where to get help, our Support and Information team is available by phone, email or live-chat.

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