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Side effects of Temozolomide

Like all chemotherapy drugs, TMZ may cause one or more side-effects. 

The most common side-effect of this drug is an increased risk of developing a form of pneumonia known as Pneumonocystis Jirovecii Pneumonia or PCP. This is a fungal infection of the lungs which people with weakened immune systems are particularly susceptible to.For this reason your oncologist may prescribe a preventative antibiotic to reduce the chance of getting this infection. Other common side-effects of this drug include:

  • Low blood count (anaemia)
  • Infection
  • Fatigue
  • Nausea and vomiting
  • Loss of appetite
  • Constipation
  • Amenorrhoea
  • Loss of fertility

For a detailed list of side-effects, please see the drug's official information leaflet at: www.medicines.org.uk/emc/medicine/7027

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